Intravenous methylprednisolone for multiple sclerosis in relapse.
نویسندگان
چکیده
A randomised comparison is made between methylprednisolone, 1 g intravenously daily for 7 days, and a standard ACTH regime for the treatment of multiple sclerosis in acute relapse. It is found that methylprednisolone produces a more rapid clinical improvement than ACTH but confers no longer term benefit when the two treatments are compared at 3 months. It is proposed that intravenous methylprednisolone does have a role to play in the management of a patient with an acute relapse of multiple sclerosis.
منابع مشابه
Methylprednisolone in multiple sclerosis: a comparison of oral with intravenous therapy at equivalent high dose.
A randomised double-blind placebo-controlled trial of intravenous methylprednisolone versus oral methylprednisolone at equivalent high dose was carried out on 35 patients with an acute relapse of multiple sclerosis (MS). After baseline evaluation each was randomly allocated to oral treatment and intravenous placebo or intravenous treatment and oral placebo, receiving 500 mg of methylprednisolon...
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عنوان ژورنال:
- Journal of neurology, neurosurgery, and psychiatry
دوره 48 2 شماره
صفحات -
تاریخ انتشار 1985